Key clinical features a general internist needs to know about Brugada syndrome: a case-based discussion
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Key clinical features a general internist needs to know about Brugada syndrome: a case-based discussion
INTRODUCTION Brugada syndrome (BrS) is an autosomal dominant genetic disorder involving the abnormal function of cardiac voltage-gated sodium ion channels. Sodium channel loss of function can lead to early repolarization and loss of the Phase 2 action potential dome in cardiomyocytes. In BrS, this sodium channelopathy occurs in some, but not all, epicardial cells thus creating 1) juxtaposition ...
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ژورنال
عنوان ژورنال: Journal of Community Hospital Internal Medicine Perspectives
سال: 2015
ISSN: 2000-9666
DOI: 10.3402/jchimp.v5.27241